Through RT-PCR, we found the aberrant splicing patterns of Anxa7, Atp2a1, Insr, MBNL1, Ldb3, CAPZB, FXR1, and MFN2 in DM1 were rescued with the ectopic miR-322/-503 expression. The gene discussed is MBNL1; the disease is myotonic dystrophy type 1.