It is reported that IL-6 can activate lncRNA DANCR through the STAT3 pathway, forming a positive feedback loop, enhancing the invasion and proliferation ability of NPC cells in vitro.153 Liu et al.154 indicated that ovatodiolide could significantly inhibit the JAK2/STAT3 signal pathway, upregulate the level of Bax and Slug and decrease the level of Bcl-xL, c-Myc, and cyclin D1, which significantly reduces the cancer stem cell characteristics of NPC cells together with survival, proliferation, invasion, migration, and EMT inhibited, and promote the apoptosis of NPC cells. The gene discussed is JAK2; the disease is nasopharyngeal carcinoma.