BLOC1S2 and Hermansky-Pudlak syndrome: We have also found as selection candidates BNC2 (among Amhara, Oromo, Wolayta and Gumuz) whose high expression is associated with dark skin colour, and BLOC1S2, encoding a subunit of the complex BLOC-1 that produces strong pigmentation phenotypes in mice and Hermansky-Pudlak syndrome in humans and also many functional enrichment categories related to UV responses.