NFKB1 and glioblastoma: In vitro studies, using both human (T98G, U87MG, T67, U373) and rat (C6) GBM cell lines, demonstrated that curcumin and curcuminoids (i.e., demethoxycurcumin (DMC)) reduce cell survival through the suppression of both NF-κB and AP-1 signaling activation.