Oncogenic levels of MYC promote high consumption of glucose as observed in most cancers, including BL [101,102,103], which correlates with the ability of MYC to regulate the expression of many genes involved in glycolysis, such as the glucose transporter SLC2A1/GLUT1, the glycolytic enzymes hexokinase 2 (HK2), triose-phosphate isomerase (TPI), enolase 1 (ENO1) and lactate dehydrogenase A (LDHA) [104,105,106]. The gene discussed is MYC; the disease is cancer.