CASP3 and Sepsis: In Galassi et al. [40], the immunoreactivity of α-SMA (α-Smooth Muscle Actin), fibronectin, MMP-9 (Matrix Metallopeptidase 9), ICAM-1, caspase-3, lactoferrin (LF), and CD15 was tested on heart samples from a control group of 25 non-sepsis cases and from a sepsis group of 56 cases in order to find out if one of them could be used as a specific marker of myocardial dysfunction in sepsis.