The expression of VEC (Vascular Endothelial-Cadherin), a Ca2+ -dependent endothelial cell–cell adhesion molecule, was investigated on lung samples by both Muller et al. [35] and Hervig et al. [36]: in the first work, immunoreactivity was tested in a control group of 20 non-sepsis patients and a group of 19 patients who died from Gram-negative sepsis; in the second work, 20 cases were patients with acute respiratory distress syndrome (ARDS) who died from Gram-negative sepsis, while 41 were control patients affected by a malignant lung tumor. Here, CDH5 is linked to acute respiratory distress syndrome.