MIR4435-2 and cancer: MIR4435-2HG is the host gene of MIR4435-2, which is considered to be a biomarker in various cancers, such as oral squamous cell carcinoma [9], non-small-cell lung cancer cells [10], prostate carcinoma [11], gastric cancer [12], hepatocellular carcinoma [13] and lung cancer [14].