In three cohorts (GSE4922-GPL96, GSE3494-GPL96 and GSE7378) [37–39] that respectively included 249 samples, 236 samples and 54 cases at different stages of breast cancer, higher TRIM28 expression was marginally associated with poorer DFS or disease-specific survival (DSS) (DFS hazard ratio [HR] = 3.62, 95% confidence interval [CI] = 2.03 to 6.44, Cox p < 0.001; DSS HR = 3.76, 95% CI = 1.77 to 7.98, Cox p < 0.001; DFS HR = 104.71, 95% CI = 6.95 to 1577.65, Cox p < 0.001; Respectively; Figure 5A–5C). The gene discussed is TRIM28; the disease is breast carcinoma.