CRP and obesity due to melanocortin 4 receptor deficiency: In this study, we included age, education level, household income, smoking status, alcohol consumption, aerobic exercise, obesity, hypertension, and diabetes as covariates; only some of these variables overlapped with those adjusted for in the Kangbuk Samsung Health Study, which included age, BMI, smoking status, alcohol consumption, liver and renal function, lipid profiles, C-reactive protein level, mean blood pressure, and glycosylated hemoglobin (HbA1c) level.