Epididymal WAT (eWAT) and GC muscle exhibited reduced expression of Cers5, Degs1, Degs2, and Smpd1 in C26‐cx mice (Figures3E–3H); the expression profile in the tumours of C26‐cx, C26‐precx, and NC26 mice was similar, showing only slightly unspecific alterations (Figure3I). Here, SMPD1 is linked to neoplasm.