Histological examination of various AD‐relevant biomarkers, including Aβ‐plaque burden, both vascular and parenchymal deposits, ionized calcium‐binding adaptor molecule 1 (Iba‐1), protein tyrosine phosphatase receptor type C (CD45), glial fibrillary acidic protein (GFAP), and glutamine synthetase (GS), was conducted on brain tissues encompassing the following regions as specified in Figure 3a: hippocampus (Hipp), cingulate cortex/retrosplenial area (Ctx), and entorhinal cortex/piriform area (Ent; Figures 3 and 4; extended data in Figures S4–S8). Here, AIF1 is linked to Alzheimer disease.