Neutropenia is a complex time-dependent [5] and a biphasic immunosuppression state in which the period of neutropenia and neutropenia recovery represents high-risk time for sepsis, acute respiratory failure (ARF), use of stimulating factors (e.g., G-CSF), pre-engraftment and engraftment syndromes [6]. The gene discussed is CSF3; the disease is Decreased total neutrophil count.