TNFRSF1B and cytomegalovirus infection: As discussed in more detail below, we found that CMV infection was associated with elevated levels of soluble TNFR2 in PWH compared to CMV-uninfected PWH [64], and a small interventional study demonstrated that inhibiting CMV replication with valganciclovir resulted in a significant reduction in plasma levels of soluble TNFR2 in PWH [65].