ISM2 and cancer: On the contrary the expression in all of other cancers was lesser; we found a moderate (2+) and diffuse positivity expression of ISM2 protein in lung adenocarcinoma (Figure 3C,D) and in prostate adenocarcinoma (Figure 3E), mild (1+) focal positivity in colon adenocarcinoma (Figure 3F), mild focal positivity in poorly cohesive carcinoma gastric (Figure 3G), and there was negativity in invasive ductal carcinoma of the breast (Figure 3H).