During EMT process, LINC01234 knockdown might suppress the expression of transcription factor Snail, and further stimulate the expression of E-cadherin, and inhibit the expressions of Vimentin and N-cadherin, which might result in a inhibition of malignant biological behaviors of ccRCC cells, such as cell proliferation, migration and invasion. This evidence concerns the gene CDH1 and nonpapillary renal cell carcinoma.