Low adiponectin concentrations are associated with insulin resistance, type 2 diabetes mellitus (T2DM), coronary artery disease, lipodystrophy, nonalcoholic hepatic steatosis, and essential hypertension, and they precede the development of insulin resistance and myocardial infarction (Swarbrick & Havel, 2008). This evidence concerns the gene ADIPOQ and Insulin resistance.