Previous reports described a number of lncRNAs (e.g., H19, MALAT1, NEAT1, TUG1, and MEG3) implicated in the development and progression of DN either via direct mediators of pathogenesis or as indirect mediators of nephropathic signaling pathways involving TNFα, TGFβ1, NF-κB, AP1, and GSK3β (Guo et al., 2019). Here, JUN is linked to liver dysplastic nodule.