SNCA and synucleinopathy: Since increased levels of phosphorylated Snca α have been associated with postoperative delirium in humans (Sunwoo et al., 2013), we also tested whether protein levels of Snca α phosphorylated at serine residue 129 [p-Snca α, a post-translationally modified form of Snca α commonly found in synucleinopathy lesions (Fujiwara et al., 2002; Kim et al., 2018)], was altered in A/S/I mice relative to controls.