Similarly, excessive levels of S-nitrosation of another multifunctional protein, Prdx2, are observed in dopaminergic neurons differentiated from induced pluripotent stem cells from PD patients as well as in PQ/MB-exposed PD mouse model and postmortem brains of patients with PD (Fang et al., 2007; Sunico et al., 2016). Here, PRDX2 is linked to Parkinson disease.