To investigate whether adipose tissues and FABP4 affect cellular energy metabolism and lipid metabolism, we examined intracellular ATP in colon cancer cells and extracellular LDH, glycerol and non-esterified fatty acid (NEFA) in culture medium supernatant after co-culture with adipose extract containing BMS309403 or not. The gene discussed is FABP4; the disease is malignant colon neoplasm.