Meanwhile, NEO1 also showed lower expression in rectal adenocarcinoma in Gaedcke dataset (fold change = -−2.949, p = 4.24E-24), in colorectal carcinoma in Hong dataset (fold change = -−1.756, p = 9.18E-13) and Skrzypczak dataset (fold change = -−2. The gene discussed is NEO1; the disease is rectum adenocarcinoma.