CCN2 and breast carcinoma: We tested if cell-ECM adhesion was altered in invasive breast cancer cells (MCF-7-EMT, MDA-MB-231) when intracellular CTGF was suppressed by RNA interference, extracellular CTGF was blocked using CTGF-specific antibodies or non-invasive MCF-7 breast cancer cells were treated with rhCTGF.