Finally, one patient (E1) with systemic lupus erythematosus who was clinically well controlled under mycophenolate mofetil but because of disabling digestive intolerance was switched to baricitinib (JAK1/2 inhibitor) at 2 mg once daily followed by 2 mg twice daily (Table 1 and Supplementary Information). Here, JAK1 is linked to systemic lupus erythematosus.