The last subclass in this group contained a mix of 237 meningiomas with a heterogeneous spectrum of mutations outside of the genes mutated in other subclasses such as NF2, TERTp, TP53, BAP1, PBRM1, AKT1, SMO and PIK3CA. The majority of tumors in this subgroup occurred in women (n = 140, 59%). Here, SMO is linked to meningioma.