TP53 and cancer: We find three UCEC PanDM-specific DMC genes that are directly associated with cancer according to the KEGG pathway annotation by DAVID [50, 51]: EI24, GNGT2, and MIR21. EI24 encodes an autophagy-associated transmembrane protein, which is a putative tumor suppressor due to its role as a downstream induction target of p53-dependent apoptosis [52].