Effects of ABCG2 and SLC2A9 polymorphisms on gout were homogenous to highly heterogeneous with I2 values of 0 to 75.2% and 39.2 to 62.9% in Asians and Caucasians for ABCG2; and 0 to 68.1% and 0 to 49.4% in Asians and Caucasians for SLC2A9 polymorphisms, see Table 1. The gene discussed is SLC2A9; the disease is gout.