In these studies, the frequency of germline pathogenic variants in BRCA1 in ovarian cancer cases were 5.1%, 3.6%, 3.7%, and 8.6%, respectively, and 3.9%, 3.3%, 4.0%, and 4.5% in BRCA2 [26,27,28,29]. The gene discussed is BRCA1; the disease is ovarian carcinoma.