RAD51C and ovarian carcinoma: More recently, Yang et al. performed a study of 125 families with pathogenic variants in RAD51C and 60 families with pathogenic variants in RAD51D and confirmed an increased risk of ovarian cancer associated with pathogenic variants in both genes (RAD51C, RR 7.55, 95% CI 5.6–10.2 and RAD51D, RR 7.6, 95% CI 5.6–10.3) [10].