TNF and sarcopenia: Fourth, The intracellular oxidative stress, one of the pathophysiology of sarcopenia, causes chronic low-grade inflammation with increased concentrations of proinflammatory cytokines such as tumor necrosis factor-alpha (TNF-α) [30,31,32] and theses cytokines may trigger to stress responses in hepatocytes, leading to TNF-α-mediated liver damage [12,30].