Individuals with human leukocyte antigen (HLA)-A3 and HLA-B8 are underrepresented in BCR-ABL+ chronic myeloid leukemia (CML) [3], and individuals with HLA-B*07, B*18, or B*40 have a lower risk of nucleophosmine-1 (NPM1)-mutant acute myeloid leukemia (AML) [4]. Here, ABL1 is linked to acute myeloid leukemia.