In a study on the interaction between hematopoietic stem and progenitor cells (HSPCs) and leukaemia mesenchymal niche, mesenchymal stromal cells (MSCs) derived from Fanconi anaemia (FA) patients with acute myeloid leukaemia (AML) (FA-AML MSCs) promoted expansion of healthy donor HSPCs, myeloid expansion of bone marrow CD34+ cells, and Treg differentiation. This evidence concerns the gene CD34 and Friedreich ataxia.