Nurr1’s role as a potential therapeutic target for bladder cancer was the subject of another study by Inamoto et al., which showed that diindolylmethane (DIM)-C-pPhCl (a new class of methylene-substituted DIM) activates the LBD of Nurr1, thereby attenuating the tumorigenic properties of bladder cancer cells [23]. Here, NR4A2 is linked to urinary bladder carcinoma.