SLC7A5 and central nervous system cancer: Furthermore, Detta and Cruickshank reported that the uptake of BPA was antagonized by pretreatment with phenylalanine or a specific inhibitor of LAT-1, and the number of LAT-1-expressing cells was three times higher than that of cells expressing proliferating cell number antigen (PCNA) in glioma patient tumor samples (71.5 ± 17.02% versus 23.8 ± 16.5%; p < 0.0001; n = 38 GBM and metastatic tumors) [11].