PAFAH1B1 and Miller-Dieker syndrome: Type-I PAF-AH is a heterotrimer composed of two catalytic α1 and α2 subunits (group XIIIA and XIIIB PLA2s, encoded by PAFAH1B2 and PAFAH1B3, respectively), and a regulatory β subunit that is identical to LIS-1, a causative gene for a type of Miller-Dieker syndrome [185].