Indeed, brain-muscle connections were also described before for the dystrophin gene [86], further extended to the autistic ADNP syndrome, with 96–100% of ADNP syndrome children suffering from motor impairments [5,8,87] and with motor impairments correlated with intellectual disability in ADNP cases [7]. This evidence concerns the gene DMD and ADNP-related multiple congenital anomalies - intellectual disability - autism spectrum disorder.