CM from both cancer cell lines induced mRNAs encoding the M2 markers CD163, FN1, and IL10 in ShCtrl THP-1 cells; the induction ranged from 2- to 4-fold by CM from MCF-7 cells (Figure 4A), and from 5- to 60-fold by CM from MDA-MB-231 cells (Figure 4B). Here, CD163 is linked to cancer.