Hence, the role of CD16+Vδ2 T cells antigens may be functionally redundant to that of other FcR+ lymphocytes such as NK cells in recognizing IgG-opsonized malaria antigens, or perhaps cytotoxic CD16+Vδ2 T cells are tailored toward particular anatomic compartments, such as the microvasculature. This evidence concerns the gene FCGR3A and malaria.