PLOD1 and Gynecomastia: Normally, LH stimulates testosterone production in the testes; how-everhuman chorionic gonadotropin (hCG), an analogue of LH, is used for its similar activity at the LH receptor; hCG is typically admin-istered as a subcutaneous injection in 1500-3000 IU equivalents 1-3 times weekly.32 The side effect profiles of GnRH and hCG are minimal with gynecomastia most commonly reported.