Based on the similarities in the WGCNA analysis between our study and previous studies32, 33, 34, 35, 37, 38 on Wnt5A expression and the potential functions, we have reason to believe that the coding genes in the ME turquoise, including MAPK13, which was also down‐regulated in PP tissues, are crucial regulators in the pathogenetic process of PAS. This evidence concerns the gene MAPK13 and gonorrhea.