Lipolysis is activated in HF due to activation of the sympathetic nervous system, renin‐angiotensin‐aldosterone system (RAAS)17, 18, 19, 20 and elevated circulating levels of natriuretic peptides A and B (ANP and BNP)11, 18 that are secreted directly by the heart.18, 19, 21. The gene discussed is NPPB; the disease is hydrops fetalis.