DUSP22 and Sepsis: In sepsis patients, JKAP level (P < 0.001) (Fig. 5a) was downregulated in deaths compared with survivors, while Th1 cell proportion (P = 0.001) (Fig. 5b) and Th17 cell proportion (P < 0.001) (Fig. 5c) were upregulated in deaths than those in survivors.