The JKAP level (P < 0.001) (Fig. 1a) was decreased in sepsis patients than that in controls; however, Th1 cell proportion (P < 0.001) (Fig. 1b) and Th17 cell proportion (P < 0.001) (Fig. 1c) were increased in sepsis patients compared with controls. This evidence concerns the gene DUSP22 and Sepsis.