The lack of difference in the immunohistochemical (IHC) staining of both the autophagy-related proteins, LC3B17 and the mitochondrial marker, TOMM20 (to assess specifically mitophagy18) between susceptible and healthy breasts suggests activation of neutral lipolysis in the breast epithelium prior to cancer diagnosis (Supplementary Fig. 4). Here, TOMM20 is linked to cancer.