Among the increased DEGs, NK2 homeobox 3 (NKX2-3) is the most upregulated gene in FT1D, and an animal study has indicated that NKX2-3 is related to T1DM [42], but further study is needed to figure out how NKX2-3 acts in FT1D. Here, NKX2-3 is linked to type 1 diabetes mellitus.