We found that the expression levels of biomarkers of CD8+ T cells (CD8A and CD8B), T cells (CD3D, CD3E, and CD2), B cells (CD19 and CD79A), monocytes (CD86 and CD115), and TAMs (CD68 and IL10) positively correlated with the expression levels of JAK3 and TYK2 in STAD. The gene discussed is CD3D; the disease is gastric adenocarcinoma.