Notably, the low C6 mRNA expression was associated with poor OS in stages 3 and 4 of HCC patients (HR = 0.37, logrank P = 0.00087) (Figure 4(e)) but was not correlated with OS of stages 1 and 2 HCC patients (HR = 0.73, logrank P = 0.27) (Figure 4(f)). This evidence concerns the gene C6 and hepatocellular carcinoma.