CD4 and acute myeloid leukemia: Contrary to Bregs, the percentages of CD4+CD25+CD127- Tregs among CD4+ T cells were higher in ND AML patients (13.77% ± 5.05%), when compared with healthy controls (8.34% ± 1.48%, P < 0.001) (Figures 1(c) and 1(d)).