The pathways closely related to the low expression of TPPP3 are “Antigen Processing and Presentation,” “Primary Immunodeficiency,” “RIG I Like Receptor Signaling Pathway,” “Endometrial Cancer,” and “P53 Signaling Pathway.” Results also indicate that TPPP3 may be related to the mechanism of tumor immunity. This evidence concerns the gene TPPP3 and endometrial cancer.