The pathways closely related to the low expression of TPPP3 are “Antigen Processing and Presentation,” “Primary Immunodeficiency,” “RIG I Like Receptor Signaling Pathway,” “Endometrial Cancer,” and “P53 Signaling Pathway.” Results also indicate that TPPP3 may be related to the mechanism of tumor immunity. The gene discussed is TP53; the disease is inborn error of immunity.