From the HCC gene expression profiles, a total of 15,186 genes were identified (fragment per kilobase million, FPKM > 1 in more than 20% samples), while the number of protein coding genes (PCGs) and lncRNA genes significantly varied between tumor tissues and NAT, as more PCGs and lncRNAs were observed in tumor tissues compared with NAT (Wilcoxon rank-sum test, P < 0.05) (Figures 1(a) and 1(b)). This evidence concerns the gene BRD2 and hepatocellular carcinoma.