E2F1 and breast cancer: We also found that several reporter regulatory molecules (e.g., E2F1, TP53, PTTG1, ZBTB16, hsa-miR-340-5p, hsa-miR-130a-3p, hsa-miR-200b-3p, hsa-miR-204-5p) regulated the transcription or post-transcription of hub genes associated with major biological processes and pathways in breast cancer, and they were also related to the OS of breast cancer patients.