We built a predictive model for CRS1 with two variables, plasma NGAL and creatinine D1, by the equation: Odds ratio ey, where y = −2.39 + 0.0037 × NGAL + 0.17 × creatinine D1 and nomogram, as shown in Figure 3. The gene discussed is LCN2; the disease is TWIST1-related craniosynostosis.