CLDN5 and cancer: Based on the marker genes, we identified the cells as eight cell types (Fig. 1e–f), namely cancer cells (EPCAM; clusters 2, 5, 10, and 11), fibroblasts (COL1A1; cluster 7), endothelial cells (CLDN5; cluster 9), T cells (CD3D; clusters 0 and 3), B cells (CD79A; cluster 12), NK cells (NKG7; cluster 4), mast cells (MS4A2; cluster 8), and myeloid cells (LYZ; clusters 1 and 6).