In GO BP analysis, the 144 potential therapeutic targets of XBJ involved multiple inflammation- and immune-related BPs such as extracellular signal-regulated kinase 1 and 2 (ERK1, ERK2) cascade, the T-cell receptor signaling pathway, activation of MAPK activity, and cellular response to LPS. Here, MAPK1 is linked to Bartsocas-Papas syndrome 1.